Publications by authors named "P J Cordero"
Article Synopsis
- - RNA-Puzzles is a collaborative project focused on improving the prediction of RNA three-dimensional structures, with predictions made by modeling groups before experimental structures are published.
- - A significant set of predictions was made by 18 groups for 23 different RNA structures, including various elements like ribozymes and aptamers.
- - The study highlights key challenges in RNA modeling, such as identifying helix pairs and ensuring proper stacking, and notes that some top-performing groups also excelled in a separate competition (CASP15).
Article Synopsis
- Environmental enrichment, consisting of physical structures and social interactions, significantly enhances broiler welfare in intensive farming settings.
- The study analyzed different behaviors, health indicators, and growth metrics over 43 days, revealing that social interactions led to increased feeding time, drinking, and foraging behaviors, while also suggesting better overall affective states in the broilers.
- Despite variations in specific behaviors, both physical and social treatments showed no negative impact on growth performance, highlighting a practical method to improve broiler quality of life without sacrificing productivity.
Insights into electron transfer and bifurcation of the Synechocystis sp. PCC6803 hydrogenase reductase module.
Biochim Biophys Acta Bioenerg
January 2025
The NAD-reducing soluble [NiFe] hydrogenase (SH) is the key enzyme for production and consumption of molecular hydrogen (H) in Synechocystis sp. PCC6803. In this study, we focused on the reductase module of the SynSH and investigated the structural and functional aspects of its subunits, particularly the so far elusive role of HoxE.
View Article and Find Full Text PDFDespite the increasing demand for efficient and sustainable chemical processes, the development of scalable systems using biocatalysis for fine chemical production remains a significant challenge. We have developed a scalable flow system using immobilized enzymes to facilitate flavin-dependent biocatalysis, targeting as a proof-of-concept asymmetric alkene reduction. The system integrates a flavin-dependent Old Yellow Enzyme (OYE) and a soluble hydrogenase to enable H-driven regeneration of the OYE cofactor FMNH.
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