Publications by authors named "P J Chase"
Article Synopsis
- Smokeless oral nicotine products are addictive and can negatively impact cardiovascular health, particularly in individuals with pre-existing heart or cerebrovascular conditions, and can also increase the risk of oral cancer depending on their chemical composition.
- The market for these products has rapidly expanded since the last American Heart Association policy, particularly with the rise of tobacco-free oral nicotine pouches, but their health effects remain unstudied.
- There is a need for strong public policies to help end tobacco addiction, focusing on preventing initiation and promoting cessation through established treatment options.
Introduction: We sought to develop clinical guidelines within our multidisciplinary Breast Center to support decision-making for managing high-risk breast lesions. The objective is to describe the process used to develop these guidelines and assess perceived acceptability.
Methods: We recruited clinical stakeholders to identify key "high-risk" topics.
Background: Residency choice is often influenced by experiences in medical school. It is unclear what potential factors contribute to medical schools producing higher numbers of physical medicine & rehabilitation (PM&R) residents.
Objective: To identify the medical schools producing the most PM&R residents from 2017 to 2021 and potential influencing factors toward this production.
Older adults are vulnerable to glucocorticoid-induced muscle atrophy and weakness, with sex potentially influencing their susceptibility to those effects. Aerobic exercise can reduce glucocorticoid-induced muscle atrophy in young rodents. However, it is unknown whether aerobic exercise can prevent glucocorticoid myopathy in aged muscle.
View Article and Find Full Text PDFPost-translational modifications of vertebrate striated muscle myosin heavy chains.
Cytoskeleton (Hoboken)
December 2024
Article Synopsis
- Post-translational modifications (PTMs) are essential for the regulation of sarcomeric proteins, particularly myosins, which are key for muscle contraction and cell motility.
- Myosin consists of two heavy chains and two pairs of light chains, with specific regions prone to PTMs that can influence their function.
- Dysregulation of these PTMs can lead to muscle dysfunction and contribute to diseases like myopathies and cardiovascular disorders, making their study important for understanding muscle physiology.