Publications by authors named "P Incagnoli"
Background: Stress due to surgical trauma decreases postoperative lymphocyte counts (LCs), potentially favouring the occurrence of postoperative infections (PIs).
Objectives: We aimed to determine whether postoperative lymphopaenia following thoracic or gastrointestinal cancer surgery is an independent risk factor for PIs and to identify modifiable factors related to anaesthesia and surgical procedures that might affect its occurrence.
Study Design: The EVALYMPH study was a prospective, multicentre cohort study with a 30-day patient follow-up.
Article Synopsis
- Optimal management of community-acquired intra-abdominal infections (IAI) involves quick surgical intervention and proper antibiotic treatment, with a focus on how timing affects patient outcomes.
- Conducted across 13 teaching hospitals in France with 205 adult patients, the study measured factors like hospital stay length and mortality rates related to treatment timings.
- Key findings indicated that delays in surgical source control, higher severity scores, and older age significantly influenced both longer hospital stays and increased risk of 28-day mortality.
Which injured patients with moderate fibrinogen deficit need fibrinogen supplementation?
Scand J Trauma Resusc Emerg Med
December 2021
Article Synopsis
- The study investigates the criteria for administering fibrinogen to patients with moderate fibrinogen deficit (MFD) following severe injuries, specifically looking at admission characteristics that correlate with fibrinogen use within 24 hours.
- Out of 1076 patients, 266 were found to have MFD-C (fibrinogen levels between 1.51-1.99 g/L), with nearly half of these patients receiving fibrinogen, particularly those with more severe injuries and compromised vital signs.
- The analysis identified that certain admission parameters, like shock index and hemoglobin levels, significantly influenced the likelihood of receiving fibrinogen, suggesting a clear relationship between these factors and the severity of the patient's condition.
Article Synopsis
- Amikacin is still a recommended antibiotic for emergency surgeries, especially for intra-abdominal infections, with current guidelines suggesting a dose of 15-20 mg/kg per day.
- A study analyzed data from 84 patients over 2.5 years to see how well they achieved target drug concentrations, finding that 32% did not, primarily due to lower doses.
- The study suggests that a fixed initial dose of 2500 mg of amikacin could optimize treatment and improve patient outcomes in emergency surgical settings.
Article Synopsis
- The study focused on how nurses in the Postanesthesia Care Unit (PACU) handle task interruptions (TI), which lead to multitasking or task-switching.
- It documented the responses of 18 nurses over 132 hours, finding that most interruptions resulted in concurrent multitasking, particularly when interruptions were brief (one minute or less).
- The research identified key predictors influencing nurse reactions to TI, suggesting new strategies for managing interruptions to improve workflow in high-pressure environments like PACU.