[Evaluation of motivational factors of adolescent patients for orthodontic treatment using the Q methodology].

The management of adolescents in the orthodontic practice remains a challenge in terms of motivation and adherence to treatment. Some factors seem to be of paramount importance in the success of treatment. The objective of the present study was to evaluate the motivational factors of adolescent patients seeking orthodontic treatment using the Q methodology.

Variable selection with Group LASSO approach: Application to Cox regression with frailty model.

In analysis of survival outcomes supplemented with both clinical information and high-dimensional gene expression data, use of the traditional Cox proportional hazards model fails to meet some emerging needs in biomedical research. First, the number of covariates is generally much larger the sample size. Secondly, predicting an outcome based on individual gene expression is inadequate because multiple biological processes and functional pathways regulate phenotypic expression.

Absence of association between polymorphisms in the pfcoronin and pfk13 genes and the presence of Plasmodium falciparum parasites after treatment with artemisinin derivatives in Senegal.

Due to resistance to chloroquine and sulfadoxine/pyrimethamine, treatment for uncomplicated Plasmodium falciparum malaria switched to artemisinin-based combination therapy (ACT) in 2006 in Senegal. Several mutations in the gene encoding the kelch13 helix (pfk13-propeller) have been identified as associated with in vitro and in vivo artemisinin resistance in Southeast Asia. Additionally, three mutations in the pfcoronin gene (G50E, R100K and E107V) have been identified in two culture-adapted Senegalese field isolates that became resistant in vitro to artemisinin after 4 years of intermittent selection with dihydroartemisinin.

Orthopantomographic analysis of the intraosseus position of the maxillary canines.

The aim of this work was to analyse the intraosseous position of the maxillary canine in orthodontic patients. It was an exploratory pilot study prior to the next research work to develop a predictive model based on a regression analysis initially including a large number of variables. 105 subjects from 6 to 12 years from both genders were included in this study.