Divergence of discrete- versus continuous-time calculations of the temperature dependence of maximum population growth rate.

The temperature dependence of population fitness is key to predicting ectotherm responses to climatic change. Discrete-time matrix projection models (MPMs) are used to calculate because they capture variation in its underlying life-history trait values and time delays inherent in those traits. However, MPM calculations can be laborious and do not capture time's continuous nature.

Financial Stress Amongst People Who Self-Harm in Sri Lanka.

Objective: Socioeconomic status deprivation is known to be associated with self-harm in Western countries but there is less information about this association in Low and Middle Income Countries (LMIC). One way of investigating this is to assess the prevalence of indicators of financial stress in people who self-harm. We have assessed the prevalence and correlates of day-to-day financial hardships amongst individual presenting with non-fatal self-harm to hospitals in Sri Lanka.

Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide.

Erythropoietin-producing hepatocellular receptor A2 (EphA2), is a receptor tyrosine kinase involved in cell-cell interactions. It is known to be overexpressed in various tumors and is associated with poor prognosis. EphA2 has been proposed as a target for theranostic applications.

Collaborative care approaches for people with severe mental illness.

Background: Collaborative care for severe mental illness (SMI) is a community-based intervention that promotes interdisciplinary working across primary and secondary care. Collaborative care interventions aim to improve the physical and/or mental health care of individuals with SMI. This is an update of a 2013 Cochrane review, based on new searches of the literature, which includes an additional seven studies.