Publications by authors named "P Hrycaj"
Article Synopsis
- The study aimed to show that CT-P47 is as effective as the EU-approved tocilizumab (r-TCZ) in treating rheumatoid arthritis (RA) patients.
- Conducted as a double-blind, phase III trial, 471 patients were randomized to receive either CT-P47 or r-TCZ, with efficacy measured primarily through changes in Disease Activity Score at specified weeks.
- Results indicated that both treatments had similar efficacy, pharmacokinetics, safety, and immunogenicity profiles, confirming CT-P47's equivalence to r-TCZ even after patients switched from r-TCZ to CT-P47.
: 25-hydroxy vitamin D (25-OH-D) is a fat-soluble compound that plays many essential functions, including bone formation, neuromuscular functions, and prevention of osteoporosis and inflammation. Recent data indicate that its metabolites are associated with rheumatoid arthritis (RA) progression and neuropathic pain in RA patients. We aimed to assess the effect of RA pharmacotherapy and seasonal variation on serum levels of 25-OH-D in RA patients who received treatment with methotrexate (MTX) or leflunomide (LEF) for at least one year.
View Article and Find Full Text PDFCelebrity-related events have influenced public interest in diseases like cancer, but their impact on rheumatic diseases is poorly investigated. We aimed to investigate whether celebrity-related events may account for atypical interest among Google users in rheumatic diseases. We used Google Trends to generate the relative search volume of 24 adult rheumatic diseases.
View Article and Find Full Text PDFIntroduction: Patients with rheumatic diseases may require costly treatment and continuous rehabilitation, which Internet collections may finance. We aimed to characterize medical crowdfunding campaigns for the needs of Polish people with rheumatic diseases.
Material And Methods: We utilized data from the largest medical crowdfunding platform in Poland, Siepomaga.