Publications by authors named "P Housset"
Time to negative PCR conversion amongst high-risk patients with mild-to-moderate Omicron BA.1 and BA.2 COVID-19 treated with sotrovimab or nirmatrelvir.
Guillaume Martin-Blondel Anne-Geneviève Marcelin Cathia Soulié Sofia Kaisaridi Clovis Lusivika-Nzinga Pierre Housset
Clin Microbiol Infect
April 2023
Article Synopsis
- - The study aimed to compare the outcomes of patients infected with Omicron BA.1 and BA.2 who were treated with either sotrovimab or nirmatrelvir to prevent severe COVID-19.
- - Of the 255 patients analyzed, nirmatrelvir resulted in faster negative PCR conversion (4 days) compared to sotrovimab (11.5 days), and a lower hospitalization rate was observed in nirmatrelvir-treated patients.
- - The findings suggest that nirmatrelvir may lead to quicker viral clearance than sotrovimab in high-risk patients, potentially reducing the spread of the virus.