Publications by authors named "P Holme"
Postdoc publications and citations link to academic retention and faculty success.
Proc Natl Acad Sci U S A
January 2025
Postdoctoral training is a career stage often described as a demanding and anxiety-laden time when many promising PhDs see their academic dreams slip away due to circumstances beyond their control. We use a unique dataset of academic publishing and careers to chart the more or less successful postdoctoral paths. We build a measure of academic success on the citation patterns two to five years into a faculty career.
View Article and Find Full Text PDFBackground: The impact of nonneutralizing antibodies (NNAs) in moderate hemophilia is elusive.
Objectives: To explore the presence of NNAs in Nordic persons with moderate hemophilia A (MHA) and B (MHB) in relation to treatment modality, clinical outcome, history of inhibitor, and the corresponding factor VIII (FVIII)/factor IX (FIX) gene mutation.
Methods: A cross-sectional multicenter study covering persons with MHA and MHB in Sweden, Finland, and Norway.
Article Synopsis
- Stylized experiments like the public goods game show that people tend to cooperate more than what traditional economic theories predict.
- There are two main explanations for this behavior: the prosocial preference hypothesis suggests cooperation is an innate trait, while the confused learner hypothesis argues it's a temporary effect during the game.
- Our research, which involved large-scale data on the prisoner's dilemma, found that while people do have a tendency to cooperate, it’s not absolute; this understanding challenges oversimplified views of cooperation and has important implications for policy.
Objectives: The 24-month, prospective, non-interventional, European multicenter A-SURE study evaluated the real-world effectiveness of prophylaxis using an extended half-life recombinant factor VIII (FVIII) Fc fusion protein, efmoroctocog alfa (hereinafter rFVIIIFc), compared with prophylaxis using standard half-life (SHL) FVIII products in patients with hemophilia A.
Methods: Primary endpoints were annualized bleeding rate (ABR), annualized injection frequency, and annualized factor consumption. A comparative study design unique for an observational hemophilia study was implemented to reduce potential confounding in effectiveness estimates, wherein each patient prescribed rFVIIIFc was matched with one receiving SHL FVIII.