Quantitative ultrasound imaging reveals distinct fracture-associated differences in tibial intracortical pore morphology and viscoelastic properties in aged individuals with and without diabetes mellitus - an exploratory study.

Introduction: Diabetes mellitus (DM) is a chronic metabolic disorder that increases fragility fracture risk. Conventional DXA-based areal bone mineral density (aBMD) assessments often underestimate this risk. Cortical Backscatter (CortBS) ultrasound, a radiation-free technique, non-invasively analyzes cortical bone's viscoelastic and microstructural properties.

Antibody Levels from High-Throughput Variant-Specific SARS-CoV-2 Anti-Spike IgG and ACE2 Neutralization Assays Correlate with COVID Infection Risk in a Large Population.

Background: SARS-CoV-2 antibody levels have been proposed as a correlate of protection (CoP) from infection. Yet, large-scale prospective studies of cost-effective scalable antibody measures as predictors of infection under real-world conditions are limited. We examined whether antibody levels measured using high-throughput variant-specific SARS-CoV-2 anti-spike immunoglobulin G (IgG) and ACE2-neutralization assays correlate with cell-based neutralizing antibody (NAb) measurements, and whether they can serve as a reasonable CoP from SARS-CoV-2 infection.

Consumer sleep technology use in individuals with obstructive sleep apnea: does it have a role in monitoring treatment response?

Consumer sleep technology (CST) has an emerging role in monitoring sleep, including screening or surveillance of sleep disorders; however, few data are available on CST in patients with obstructive sleep apnea (OSA). We analyzed attitudes towards CST and patterns of CST use among individuals with OSA. Among 251 respondents (mean age 57.

Emil Kraepelin and Walter Benjamin: distant contemporaries, diverse working methods, any resonance?

The work methods of eminent psychiatrist Emil Kraepelin (1856-1926) and of literary and cultural critic Walter Benjamin (1892-1940) are described based on the literature describing their ways of working. Kraepelin's approach of cross-sectional observation of symptoms and the longitudinal study of illness course in distinguishing 'disease entities' as well as his research strategy of investigating causes and correlates using methods of experimental psychology, pathology and neurobiology are described. Critical statements (on Kraepelin's work) highlighting preconceived concepts, ideological positions and a lack of critical reflection are reported.

What kind of «thing» is mental illness? Listening to Kraepelin, Jaspers and Kronfeld.

Since its beginnings psychiatry controversely debated about the appropriate concept of illness, about nosology and the diagnostic terms and procedures based upon it. This paper discusses the approaches introduced by Emil Kraepelin (1856-1926), Karl Jaspers (1883-1969) and Arthur Kronfeld (1886-1941). Whereas Kraepelin postulated the existence of «natural entities» with regard to mental illness, Jaspers acknowledged the heuristic value of the term «disease entity», but declared it a «regulative idea» in a Kantian sense, i.