Publications by authors named "P Hewitson"
Article Synopsis
- - Propolis, a complex resin produced by bees, varies in composition based on the plants the bees visit, and red Brazilian propolis shows promising antimicrobial properties that need further investigation.
- - This study aimed to refine a method to efficiently extract and isolate beneficial compounds from red propolis using counter-current chromatography and preparative HPLC, addressing issues like wax removal that can clog equipment.
- - The researchers successfully isolated three key compounds linked to red propolis's therapeutic effects, identifying them as retusapurpurin A, 3()-7-O-methylvestitol, and xanthochymol/isoxanthochymol, which will aid in future biological testing and serve as standards in chromatography.
Objectives: Measuring patient experience of gastrointestinal (GI) procedures is a key component of evaluation of quality of care. Current measures of patient experience within GI endoscopy are largely clinician derived and measured; however, these do not fully represent the experiences of patients themselves. It is important to measure the entirety of experience and not just experience directly during the procedure.
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- * Traditional cell lysates require purification methods, like caesium chloride or chromatography, but have limitations such as poor infectiousness and restricted storage capability.
- * An innovative aqueous two-phase system (ATPS) using 20% PEG 600 and 20% (NH)SO has been shown to efficiently purify AdVs, yielding over 97% high-titre virus with no cytotoxic effects, and stable storage at -20 °C or 4 °C for future clinical
The detailed metabolite profiling of was accomplished by high-performance countercurrent chromatography (HPCCC) using the three-phase system -hexane--butyl methyl ether-acetonitrile-water 2:3:3:2 (///) in step-gradient elution mode. The gradient elution was adjusted to the chemical complexity of the ethyl acetate partition and strongly improved the polarity range of chromatography. The three-phase solvent system was chosen for the gradient to avoid equilibrium problems when changing mobile phase compositions encountered between the gradient steps.
View Article and Find Full Text PDFBackground: Measuring patient experience is important for evaluating the quality of patient care, identifying aspects requiring improvement and optimising patient outcomes. Patient Reported Experience Measures (PREMs) should, ideally, be patient derived, however no such PREMs for gastrointestinal (GI) endoscopy exist. This study explored the experiences of patients undergoing GI endoscopy and CT colonography (CTC) in order to: identify aspects of care important to them; determine whether the same themes are relevant across investigative modalities; develop the framework for a GI endoscopy PREM.
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