Salvage Magnetic Resonance Imaging-guided Transurethral Ultrasound Ablation for Localized Radiorecurrent Prostate Cancer.

Background And Objective: Toxicity from local salvage therapy for radiorecurrent prostate cancer (PCa) remains a concern. This phase 2 study evaluates the outcomes of salvage magnetic resonance imaging (MRI)-guided transurethral ultrasound ablation (sTULSA).

Methods: Men with biochemically relapsed, biopsy-proven PCa following definitive radiotherapy underwent whole- or partial-gland sTULSA (NCT03350529).

Changes in socio-economic inequality in alcohol-attributable mortality in periods of increasing and decreasing alcohol affordability.

Introduction: Reducing alcohol affordability reduces alcohol-related harm but its impact on socio-economic inequalities requires further study. We examine changes in alcohol-attributable mortality inequalities in Finland during periods of sharply rising (2000-2007) and falling (2008-2017) alcohol affordability.

Methods: Linking individual-level register data on causes of death and socio-demographics for the Finnish population aged ≥25 in 2000-2017 (68 million person-years), we analysed age-standardised monthly alcohol-attributable mortality rates by sex and income quintile (n = 32,699 alcohol-attributable deaths).

Predator-specific mortality of sage-grouse nests based on predator DNA on eggshells.

Greater sage-grouse (hereafter sage-grouse; ) populations have declined across their range. Increased nest predation as a result of anthropogenic land use is one mechanism proposed to explain these declines. However, sage-grouse contend with a diverse suite of nest predators that vary in functional traits (e.

Actual electrolyte intake during the first week of life and morbidity in very-low-birthweight infants.

Aim: To describe sodium and potassium intake, their sources and plasma concentrations, and the association between intake and morbidity in very-low-birthweight (VLBW, <1500 g) infants during the first week of life.

Methods: This retrospective cohort study comprised 951 VLBW infants born at <32 weeks. Infants were divided into three groups according to gestational age: 23-26 (n = 275), 27-29 (n = 433) and 30-31 (n = 243) weeks.