Publications by authors named "P Hasbak"
Importance: Long-term use of anabolic androgenic steroids (AASs) is associated with a high risk of left ventricular hypertrophy, heart failure with reduced systolic function, and early sudden death, with the mechanism of progression being understudied. Early and persistent impaired myocardial microcirculation could be of clinical importance and a potential underlying mechanism of frequent and early cardiac disease among individuals with AAS use and a future potential target for intervention.
Objective: To investigate coronary microcirculation by measuring myocardial flow reserve (MFR) in men with current and former AAS use compared with controls with no prior AAS use, using cardiac rubidium 82 (82Rb) positron emission tomography/computed tomography (PET/CT).
Article Synopsis
- Infective endocarditis (IE) is a severe condition that can be fatal, particularly in patients with prosthetic valves. The study evaluates the effectiveness of a new PET tracer, [Cu]Cu-DOTATATE, for diagnosing IE.
- The case series highlights two patients: Patient 1, with a mitral valve prosthesis, showed positive tracer uptake at the infection site and had a successful surgery, while Patient 2, with an aortic valve infection, showed no uptake and experienced complications leading to death.
- This research suggests the potential diagnostic value of [Cu]Cu-DOTATATE for IE but also indicates variability in its effectiveness based on the type of valve involved.
Aims: Patients with type 2 diabetes (T2D) have a high prevalence of diastolic dysfunction and heart failure with preserved ejection fraction (HFpEF), which in turn leads to an increased risk of hospitalization and death. However, the factors of risk and their relative importance in leading to higher left ventricular filling pressures are still disputed. We sought to clarify the associations of a wide range of invasive and non-invasive risk factors with cardiac filling pressures in high-risk T2D patients.
View Article and Find Full Text PDFIn patients with chronic obstructive pulmonary disease (COPD), pulmonary vascular dysfunction and destruction are observable before the onset of detectable emphysema, but it is unknown whether this is associated with central hypovolemia. We investigated if patients with COPD have reduced pulmonary blood volume (PBV) evaluated by Rb-positron emission tomography (PET) at rest and during adenosine-induced hyperemia. This single-center retrospective cohort study assessed 6,301 Rb-PET myocardial perfusion imaging (MPI) examinations performed over a 6-yr period.
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