Subunit specific altered expression and activity of casein kinase 2 in the brain tissues resected from mesial temporal lobe epilepsy with hippocampal sclerosis patients & rodent temporal lobe epilepsy model.

Introduction: Mesial temporal lobe epilepsy (MTLE), is associated with dysregulated excitatory-inhibitory balance in the brain. Numerous enzymes, protein kinases, that are modulated through phosphorylation, have been linked with key processes involved in the pathogenesis of epilepsy. Therefore, in this study, we determined the subunit specific expression and activity of multi-subunit casein Kinase 2 (CK2) which influences NMDARs through phosphorylation events, in MTS patients as well as pilocarpine model of TLE.

Timely intervention of spontaneous scleral melt in Marfan syndrome.

A young man in his late adolescence presented with a gradually progressive diminution of vision in both eyes for 3 years. A general physical examination revealed features suggestive of Marfan syndrome, with a positive family history. Ocular examination revealed a superonasal lens subluxation with a myopic fundus in both eyes.

Psychological Effects of Orthodontic Treatment in Adults: A Mixed-Methods Study.

Background: Orthodontic treatment is often pursued to improve dental aesthetics and function, but its psychological effects on adult patients are not well-documented.

Materials And Methods: This mixed-methods study involved 150 adult participants undergoing orthodontic treatment. Quantitative data were collected using the Oral Health Impact Profile (OHIP-14) questionnaire and the State-Trait Anxiety Inventory (STAI) before treatment, mid-treatment, and posttreatment.

Biomechanical Evaluation of Different Orthodontic Archwire Materials and Their Effect on Tooth Movement Efficiency.

Background: Orthodontic treatment relies on the efficient movement of teeth, which is influenced by the material properties of archwires.

Materials And Methods: This study involved 60 patients undergoing orthodontic treatment, randomly assigned to three groups, each using a different type of archwire material: stainless steel (SS), nickel-titanium (NiTi), and beta-titanium (TMA). The evaluation was conducted over 6 months, measuring tooth movement efficiency, force delivery, and patient discomfort.

A Comparative Evaluation of Antimicrobial Efficacy of Five Different Herbal Solutions: Propolis, Azadirachta Indica (Neem), Triphala, Green Tea, and Turmeric against Enterococcus Faecalis and Debris Removal from the Root Canal Using Two Irrigation Protocols-Manual and Ultrasonic-An Study.

Aim: To assess the objectives are to assess and contrast the antibacterial activity of neem, propolis, triphala, turmeric, and green tea as well as the effectiveness of these substances in clearing root canal debris in the presence and absence of passive ultrasonic irrigation.

Methodology: Techniques, such as neem, propolis, triphala, turmeric, and green tea, were tested for antibacterial activity using enterococcus faecalis (ATCC-24212) as a test organism and an agar diffusion test. The negative control group was saline.