Publications by authors named "P H Schipper"
Anterior segment OCT for imaging PAUL glaucoma implant patch grafts: a useful method for follow-up and risk management.
Graefes Arch Clin Exp Ophthalmol
December 2024
Aim: To evaluate a useful, non-contact method for the follow-up of pericardium patch graft changes in patients undergoing PAUL Glaucoma Implant (PGI) surgery using high-resolution anterior segment optical coherence tomography (OCT) to predict tube erosions.
Methods: Prospective analysis over six months of tube pericardium patch graft thickness of PGI surgical cases at the University Eye Hospital Bonn, Germany, from November 2021 to August 2022. In all eyes, Tutopatch (RTI Surgical, United States) pericardium was used to cover the implant intra-operatively.
Background: Before lung cancer resection, patients inquire about dyspnea and the potential need for supplemental oxygen. The objective of this study was to identify predictors of discharge with supplemental oxygen for patients undergoing lobectomy for lung cancer.
Methods: Using The Society of Thoracic Surgeons General Thoracic Surgery Database, study investigators conducted a retrospective cohort study of patients who underwent lobectomy for lung cancer from July 2018 to December 2021.
Article Synopsis
- HIV persists in the central nervous system (CNS) of people living with HIV, leading to cognitive impairments even with antiretroviral therapy (ART).
- Researchers analyzed paired cerebrospinal fluid (CSF) and blood samples from 19 untreated adults, finding higher HIV RNA levels in plasma compared to CSF and mostly consistent coreceptor usage.
- The study revealed that some viruses in the CNS can replicate in microglia (brain immune cells) as well as T-cells, suggesting that viral evolution may help the infection spread within the CNS, which needs further investigation.
The central serotoninergic system is critical for stress responsivity and social behavior, and its dysregulations have been centrally implicated in virtually all neuropsychiatric disorders. Genetic serotonin depletion animal models could provide a tool to elucidate the causes and mechanisms of diseases and to develop new treatment approaches. Previously, mice lacking tryptophan hydroxylase 2 (Tph2) have been developed, showing altered behaviors and neurotransmission.
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