Publications by authors named "P H Savelkoul"
Unlabelled: Current laboratory protocols for periprosthetic joint infections (PJIs) involve a standard 10- to 14-day incubation period. However, recent evidence indicates considerable variability in the time to diagnosis (TTD) between acute and chronic PJIs. TTD is also influenced by the employed culture media and sample types.
View Article and Find Full Text PDFThe human intestinal tract contains trillions of bacteria that coexist in a symbiotic relationship with human cells. Imbalances in this interaction can lead to disorders such as Crohn's disease (CD). Bacteria membrane vesicles (MVs), which are released by almost all bacteria, have been demonstrated to play a crucial role in bacteria-host interactions.
View Article and Find Full Text PDFArticle Synopsis
- The urogenital microbiota is recognized as an important factor in reproductive health, potentially influencing fertility treatment outcomes.
- A study was conducted with women aged 20-44 who were subfertile and preparing for IVF, analyzing both urine and vaginal samples collected by the patients.
- Results showed a strong correlation in microbiota profiles between samples, but the urinary microbiota had fewer species, suggesting that vaginal samples may provide more valuable insights for predicting fertility treatment success.
Objectives: The COVID-19 pandemic highlights the importance of understanding facilitators for disease transmission. Events such as Carnival, characterized by large gatherings and extensive social interactions, have the potential to become 'super spreading events' for respiratory infections. This paper aims to assess the impact of large gatherings on virus transmission, providing crucial insights for the development of effective public health strategies.
View Article and Find Full Text PDFComparing visual and automated urine dipstick analysis in a general practice population.
Scand J Prim Health Care
August 2024
Article Synopsis
- Urinary symptoms are a common reason for women to seek medical advice, and urinary dipstick tests are key for diagnosing UTIs, though visual readings can be inconsistent.
- A study compared visual versus automated dipstick interpretations using 302 urine samples and found almost perfect agreement for nitrite and leukocyte esterase, but moderate for erythrocytes, and both methods had similar sensitivity and specificity for predicting bacteriuria.
- While both methods were effective, automated analysis had potential maintenance issues and occasional measurement errors, despite nearing perfect agreement with visual readings.