Mixed cryoglobulinemia: clinical aspects and long-term follow-up of 40 patients.

The clinical course of 40 patients with significant quantities of mixed cryoglobulins, but without lymphoproliferative, collagen-vascular or chronic infectious diseases, is presented. These cases comprise 51.3 percent of all mixed and 31.

Morphogenesis of rabbit fibroma virus. Correlation with pathogenesis of the skin lesion.

Rabbit fibroma virus injected into the dermis of adult rabbit skin evokes an inflammatory, then granulomatous and finally proliferative or tumoral response. About 1 week after injection, the grossly visible nodular lesion reaches its maximum size and regresses, becoming hemorrhagic and necrotic. Unlike vacciiia, the morphogenesis of the RFV has not been validated satisfactorily.

The uptake of a labeled double-stranded polynucleotide by cultured rabbit kidney cells: an electron microscopic study.

Polyribocytidylate-(3)H-polyriboinosinate (rC-(3)H:rI) enters cultured rabbit kidney cells from the surrounding medium within (1/2) hr after exposure. Grains are found in the cytoplasm, nucleus, and nucleolus. At 2 hr, grains are localized predominantly over the nucleolar regions.