IEEE Trans Neural Netw
March 2006
In this paper, we propose a new pruning algorithm to obtain the optimal number of hidden units of a single layer of a fully connected neural network (NN). The technique relies on a global sensitivity analysis of model output. The relevance of the hidden nodes is determined by analysing the Fourier decomposition of the variance of the model output.
View Article and Find Full Text PDFAccid Anal Prev
March 2006
To reduce the number and the gravity of accidents, it is necessary to analyse and reconstruct them. Accident modelling requires the modelling of the impact which in turn requires the estimation of the deformation energy. There are several tools available to evaluate the deformation energy absorbed by a vehicle during an impact.
View Article and Find Full Text PDFBACKGROUND: Superficial cellulitis (erysipelas) of the leg is a frequent infectious disease with a favorable outcome, whereas some patients present a serious disease. The determinants of severity for superficial cellulitis (erysipelas) of the leg have not yet been clearly established. In order to determine the characteristics of patients presenting with severe superficial cellulitis of the leg, we analyzed patients with favorable and unfavorable outcome.
View Article and Find Full Text PDFIntroduction: The official policy of the French National Health Insurance system is to deny reimbursement for drugs prescribed for off-label indications. The objectives of this study were 1) to quantify the use of off-label prescriptions by physicians from a hospital department of dermatology in France; 2) to characterize these off-label prescriptions; 3) to assess data from the literature on the appropriateness of these off-label prescriptions.
Patients And Methods: For each patient consulting between February 1 and April 1, 2001, the symptom or the disease that was treated and the type of prescription were recorded on standard forms.
Background: This study addressed the question of whether limited surgery for primary malignant melanoma with a 2-cm margin is as good as a 5-cm margin. An update of a 16-year follow-up is provided.
Methods: Nine European Centers, over a period of 5 years, prospectively randomized 337 patients with melanoma measuring less than 2.