Publications by authors named "P H Kuijper"
Article Synopsis
- The study examines the effectiveness of reference intervals (RIs) in clinical decision-making while accounting for analytical biases in Dutch laboratories for three different measurements: creatinine, hemoglobin, and ferritin.
- Data was collected from quality assessments and reported RIs, which were compared to harmonized RIs to evaluate their consistency with analytical bias.
- Results indicated a lack of consistency in routinely used RIs and their analytical bias, highlighting that adopting harmonized RIs could improve inter-laboratory decision-making and reduce misinterpretations in patient diagnoses.
Light transmission aggregometry (LTA) is considered the gold standard method for evaluation of platelet function. However, there are a lot of variation in protocols (pre-analytical procedures and agonist concentrations) and results. The aim of our study was to establish a national LTA protocol, to investigate the effect of standardization and to define national reference values for LTA.
View Article and Find Full Text PDFBackground: Given the excellent performance of modern mass spectrometers, their clinical application for the analysis of macromolecules is a growing field of interest. This principle is explored by hemoglobin analysis, which is a representative example by its molecular weight and clinical relevance in e.g.
View Article and Find Full Text PDFBackground: Therapeutic drug monitoring (TDM) of infliximab (IFX, Remicade®) can aid to optimize therapy efficacy. Many assays are available for this purpose. However, a reference standard is lacking.
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