Publications by authors named "P H Kindling"
Article Synopsis
- Following high doses of methionine, a degradation product called homocysteine (HC) significantly increases in the serum of both normotensive (NR) and spontaneously hypertensive (SHR) rats, leading to harmful effects on the aorta, especially in SHR.
- The aortic damage is characterized by massive endothelium loss, mitochondrial degeneration, and increased levels of HC and cystathion (CT) specifically in SHR, where these effects are more pronounced and develop faster than in NR.
- Additionally, the presence of atherogenic substances intensifies the aortic damage in SHR but does not have the same effect in NR, highlighting the critical role of altered protein metabolism, alongside fat and carbohydrate metabolism, as risk factors for vascular
A series of forty-six flexor-tendon grafts in forty-one patients is evaluated. All of these patients presented less-than-optimum situations for tendon-grafting due to persistent joint stiffness, deep cicatrix, preliminary skin-grafting procedures, nerve damage, or severe multiple injuries.The results show a worth-while gain of flexion in the proximal interphalangeal joint of the fingers, but a poor gain in the distal interphalangeal joint.
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