Publications by authors named "P H Beaudry"
Objective: Decision-making about antireflux procedures (ARPs) to treat gastroesophageal reflux disease in children with neurologic impairment and gastrostomy tubes is challenging and likely influenced by physicians' experience and perspectives. This study will explore physician attitudes about ARPs and determine if there are relationships to clinical practice and personal characteristics.
Methods: This is a national observational cross-sectional study that used an electronic questionnaire addressing reported practice, attitudes regarding the ARPs, and responses to clinical vignettes.
Article Synopsis
- Human prion diseases are severe neurodegenerative conditions with sporadic, infectious, and genetic forms, with the E200K mutation being a common genetic variant of Creutzfeldt-Jakob disease, which has no existing treatments.
- Researchers created a genetic model using the nematode Caenorhabditis elegans to study the effects of the E200K prion protein mutation on neuronal health and behavior, revealing neurodegeneration and misfolding patterns.
- This model helped identify five existing FDA-approved compounds that could combat the harmful effects of the E200K prion protein, advancing the research in prion disease therapies.
Background: In 2017, a provincial guideline was created to fast track and standardize care for pediatric appendicitis in Alberta. We conducted a study to determine the impact of implementation of the guideline at our institution on length of stay (LOS), antibiotic stewardship efforts and costs.
Methods: We performed a retrospective review of the charts of all patients younger than 18 years of age who underwent appendectomy at our institution in 2 periods: before guideline implementation (Dec.