Publications by authors named "P Gutknecht"

Introduction: The growing population of heart failure (HF) patients places a burden on the healthcare system. Patient-centered outcomes such as health-related quality of life (HRQoL) and self-care behaviors are key elements of modern HF management programs. Thus, optimized strategies to improve these outcomes are sought.

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  • Employees of uniformed services (EoUS) were found to have significantly higher cardiovascular risk factors compared to controls, including blood pressure, cholesterol, and BMI.
  • A study conducted in Gdańsk, Poland, involving 1138 EoUS and 263 controls revealed that EoUS had more instances of high blood pressure, elevated cholesterol levels, and a higher percentage of smokers, particularly in younger ages.
  • The calculated ten-year risk of fatal cardiovascular events was also higher in the EoUS group, indicating a greater overall risk for cardiovascular issues among this population.
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  • Renal cell carcinoma (RCC) lacks specific diagnostic methods and treatments, necessitating the evaluation of new diagnostic tools and treatment options.
  • This study utilized multiplatform untargeted metabolomics analysis of urine from RCC patients and healthy volunteers to identify unique metabolic patterns associated with RCC and its subtype, clear cell renal cell carcinoma (ccRCC).
  • Analyses revealed two panels of specific metabolites linked to RCC, highlighting disruptions in amino acid, lipid, and purine metabolism, with notable findings in modified nucleosides and significant changes in symmetric dimethylarginine (SDMA) levels in RCC patients.
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Introduction And Objective: Difficult-to-control blood pressure can be attributed to a mismatch between the haemodynamic type of hypertension and the drug class used in treatment. Impedance cardiography may be a useful tool for enabling the individualization of antihypertensive therapy. The aim was to investigate the distribution of haemodynamic types of HT among hypertensive patients in an outpatient clinic.

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Aim: Prevention of heart failure (HF) hospitalisations and deaths constitutes a major therapeutic aim in patients with HF. The role of telemedicine in this context remains equivocal. We investigated whether an outpatient telecare based on nurse-led non-invasive assessments supporting remote therapeutic decisions (AMULET telecare) could improve clinical outcomes in patients after an episode of acute HF during 12-month follow-up.

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