Publications by authors named "P Gustin"
Moyamoya disease (MMD) is a chronic, occlusive cerebrovasculopathy typified by progressive steno-occlusive disease of the intracranial internal carotid arteries (ICAs) and their proximal branches. Moyamoya syndrome (MMS) categorizes patients with characteristic MMD plus associated conditions. As such, the most usual presentations are those that occur with cerebral ischemia, specifically transient ischemic attack, acute ischemic stroke, and seizures.
View Article and Find Full Text PDFArticle Synopsis
- * They studied blood samples from 263 horses, including those with AM, healthy horses grazing together, and others with colic, and found some key differences in their blood that could help identify AM.
- * The researchers discovered that younger geldings (castrated male horses) had a lower risk of getting AM, and a specific type of blood marker could help tell if a horse with AM would survive.
Article Synopsis
- The study explores the use of dose and volume metrics in radiotherapy planning, specifically for breast cancer patients undergoing hypofractionation and integrated boost treatments.
- It analyzes dosimetry data from 42 patients, focusing on the heart, lungs, and contralateral breast, to identify which metrics are most representative.
- The findings suggest that basic statistics like mean, standard deviation, and median doses effectively correlate with each other, indicating a simpler approach to metric selection may be sufficient for evaluating organ doses in radiotherapy.
Studies of the effects of external stimuli on bone tissue, disease transmission mechanisms, and potential medication discoveries benefit from long-term tissue viability ex vivo. By simulating the in-vivo environment, bioreactors are essential for studying bone cellular activity throughout biological processes. We present the development of an automated 3D-printed bioreactor EnduroBone designed to sustain the ex-vivo viability of 10 mm diameter cancellous bone cores for an extended period.
View Article and Find Full Text PDFIntroduction: Prompt detection of traumatic cervical spine injury is important as delayed or missed diagnosis can have disastrous consequences. Given the understood mechanism of non-accidental trauma (NAT), it is reasonable to suspect that cervical spine injury can occur. Current management of young children being evaluated for NAT includes placement of a rigid collar until clinical clearance or an MRI can be obtained.
View Article and Find Full Text PDF