Publications by authors named "P Guha"
We propose a general approach to quasi-deform the Korteweg-De Vries (KdV) equation by deforming its Hamiltonian. The standard abelianization process based on the inherent sl(2) loop algebra leads to an infinite number of anomalous conservation laws, that yield conserved charges for definite space-time parity of the solution. Judicious choice of the deformed Hamiltonian yields an integrable system with scaled parameters as well as a hierarchy of deformed systems, some of which possibly are quasi-integrable.
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- The ETERNAL-LVO trial examines the effectiveness and safety of tenecteplase for patients with large vessel occlusion (LVO) within 24 hours of stroke onset, compared to standard care.
- The study is a randomized phase 3 trial involving patients with anterior circulation LVO and target mismatch on imaging, focusing on those who may need endovascular treatment.
- Key outcomes include measuring disability at 3 months using the modified Rankin Scale, alongside safety assessments like the incidence of symptomatic intracerebral hemorrhage and overall mortality.
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- This study focuses on creating two zinc(II)-based metal-organic frameworks (MOFs) with unique structures derived from specific ligands, yielding compounds 1 and 2.
- The analysis revealed a paddle-wheel secondary building block formed from dinuclear Zn(II) centers and dicarboxylate groups, resulting in a 2D layer architecture interconnected into a 3D structure.
- Further investigations showed that these compounds have a strong affinity for DNA, indicating potential future applications as protein binders and bioactive substances.
Background: This study aimed to determine the prevalence of TB among patients living with HIV in Patna district, India. It also assessed the factors contributing to co-infection and evaluated patients' quality of life.
Methods: This cross-sectional study was conducted at the Antiretroviral Therapy (ART) Centre in Patna, India, for a period of eight months.
HDACs (histone deacetylase) play a crucial role in regulating gene expression, and the inhibition of these enzymes is gaining attention as a promising therapeutic approach for cancer treatment. Despite their significant physiological and clinical importance, the mechanisms of HDAC activation remain poorly understood. This study reveals that inositol polyphosphate multikinase (IPMK) is essential for activating HDAC1 and HDAC3 in cell lines and mice.
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