Nivolumab may induce severe celiac-like enteropathy, that may appear very rapidly, after only two injections of nivolumab, and may be successfully treated with corticosteroids. This observation underlines the importance of histological analysis of duodenal biopsies and the necessity to rule out a real celiac disease in patients with nivolumab-induced diarrhea.
View Article and Find Full Text PDFIntroduction: Neuroendocrine tumors are rare, with poor prognosis when not or poorly differentiated.
Exegesis: The authors report the case of a patient who presented with a metastatic poorly differentiated neuroendocrine tumor that was resistant to chemotherapy. The different sites of the carcinoma were lung, pancreas, kidney and lymph nodes.
Non-Hodgkin's lymphoma is common in patients with human immuno-deficiency virus infection, but an intracardiac localisation is rare. In this case, the malignant lymphoma presented with a degradation of the patient's condition and signs of right-sided cardiac failure. Echocardiography showed a polylobed mass invading the right ventricle.
View Article and Find Full Text PDFFibromatosis is a fibroblastic proliferation which has infiltrative properties and which is not expected to metastasize. Mammary fibromatosis is infrequent. Clinically, it may mimic breast carcinoma.
View Article and Find Full Text PDFRev Med Interne
February 1992
The authors report the case of a 68-year old woman with systemic mastocytosis revealed by spleen enlargement and portal hypertension, and associated with chronic myelomonocytic leukaemia. Based on their review of the literature, they describe the general characteristics of systemic mastocytosis and underline the frequent association of this disease with malignant haematological disorders, notably in the myeloid series.
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