Publications by authors named "P Guerby"

Fetal death is defined as the spontaneous cessation of cardiac activity after 14 weeks gestational age (GA). Regarding prevention of fetal death in the general population, it is not recommended to counsel or prescribe rest, aspirin, vitamin A, vitamin D, or micronutrient supplementation; systematically look for nuchal cord during prenatal screening ultrasound; or perform systematic antepartum monitoring by cardiotocography for the sole purpose of reducing the risk of fetal death. It is recommended to offer vaccination against influenza in epidemic periods and against SARS-CoV-2.

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Objectives: To estimate the association between low first-trimester maternal serum placental growth factor (PlGF) and pregnancy-associated plasma protein A (PAPP-A) and the risk of placenta-mediated complications.

Methods: We performed a secondary analysis of PREDICTION study including nulliparous participants recruited at 11-14 weeks of pregnancy. First-trimester PlGF and PAPP-A were reported in multiples of the median (MoM) adjusted for maternal characteristics and gestational age.

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Unlabelled: ST analysis during labour requires the classification of CTG traces in order to help clinical decisions. The usual STAN classification is based on the FIGO 1987 classification, modified in 2007. New STAN guidelines adapted to physiology-based interpretation have been proposed in 2022.

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Article Synopsis
  • The study aimed to determine whether a more restrictive threshold for aspirin prophylaxis (risk >1/70) would effectively identify high-risk nulliparous women for pre-eclampsia compared to the usual threshold (risk >1/100).
  • Conducted at the University Hospital of Toulouse, the study observed two cohorts: one before the screening (2014-2016) and one after implementing the FMF screening and aspirin treatment (2017-2018).
  • Results showed no significant difference in pre-eclampsia rates (1.7% vs. 1.3%) between the two groups, indicating that using the more restrictive threshold did not lead to a decrease in pre-eclampsia with premature delivery
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Fetal death is defined as the spontaneous cessation of cardiac activity after fourteen weeks of amenorrhea. In France, the prevalence of fetal death after 22 weeks is between 3.2 and 4.

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