Publications by authors named "P Gude"
To date, apart from moderate hypothermia, there are almost no adequate interventions available for neuroprotection in cases of brain damage due to cardiac arrest. Affected persons often have severe limitations in their quality of life. The aim of this study was to investigate protective properties of the active compound of dimethyl fumarate, monomethyl fumarate (MMF), on distinct regions of the central nervous system after ischemic events.
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- Emergence delirium is a common complication in young children after anesthesia, especially in those undergoing ear, nose, and throat surgeries, and is assessed using the Pediatric Assessment of Emergence Delirium (PAED) scale.
- In a study of 105 children aged 0-6, only 4.7% displayed severe emergence delirium, while 35% had some degree of it, with higher pain levels and lower blood glucose being significant risk factors.
- The results suggest that maintaining higher blood glucose and managing pain could reduce the risk of emergence delirium in pediatric patients.
Background: The Children's and Infant's Postoperative Pain Scale (CHIPPS) and the German version of the Parent's Postoperative Pain Measure (PPPM-D) are used to assess postoperative pain intensity in preschool children. However, they have shown low concordance in previous prospective studies on quality improvement.
Aims: Our secondary analysis aimed to estimate the association strength between the pain score items and indication for rescue medication defined as CHIPPS ≥4 and/or PPPD-D ≥ 6.
Background: During pediatric general anesthesia (GA) and sedation, clinicians aim to maintain physiological parameters within normal ranges. Accordingly, regional cerebral oxygen saturation (rScO) should not drop below preintervention baselines. Our study compared rScO desaturation events in children undergoing GA or chloral hydrate sedation (CHS).
View Article and Find Full Text PDFBackground: The optimal pain therapy for children undergoing tonsillotomy remains unknown. Our aim was to evaluate a standard pain therapy including the alternating application of ibuprofen and paracetamol.
Methods: Pain intensity of 81 in-patients after tonsillotomy aged 2-12 years was evaluated three times daily (mean observation 3.