[Trophoblastic tumor on the placenta. Diagnosis, prognostic factors, treatments].

Previously known under other terms, placenta site trophoblastic tumor (PSTT) is a specific entity among trophoblastic diseases. Outcome is highly variable depending on the clinical course which may range from benign disease to high-grade malignancy. Histology and biology, including mitotic count, the degree of tumor invasion, the process of necrosis within the tumor and plasma beta-hCG level, provide important indications for prognosis.

[Apert syndrome. Ultrasonic diagnosis, obstetrical management].

We report two observations of antenatal diagnosis of Apert syndrome. This uncommon genetic disorder suggest an autosomal dominant inheritance, but almost all cases described are sporadic; the responsible gene is yet not located. Ultrasonographic detection is difficult, based on the following signs: brachycephalic skull (unusually detected), flat facial profile with a nasal bridge depression, tall appearance of the forehead (inconstant), total bilateral and symmetrical syndactylies of the hands and feet.

[Uncontrolled retrospective study of 75 pregnancies in women treated for epilepsy].

Objective: Our purpose was to study pregnancies and birth outcomes in a population of women treated for epilepsy.

Study Design: A retrospective uncontrolled study of 75 pregnancies in 55 epileptic women under treatment was conducted in the nursery of CHU Angers. The course of pregnancies and deliveries, the frequency of congenital malformations and the clinical state of the neonates during the first 6 days of life were recorded.

[Serum alkaline phosphatase levels in pregnancy].

Serum levels of total alkaline phosphatase increase during pregnancy but the presently available methods are not very precise. We used the CHEM 1 Bayer Diagnostic test in all the consecutive patients admitted to our unit between June 1 and October 16, 1990. Exclusion criteria were twin pregnancies, pruritus, liver disease or parasitosis.

[Rupture of aneurysm of the splenic artery during the first three months of pregnancy].

A rare but dramatic case of haemoperitoneum of non-gynaecological origin which occurred during pregnancy is reported. Obstetrical causes of shock having been excluded, laparotomy made it possible to discover an aneurysm of the splenic artery and treat it by resection-ligation and splenectomy. In such cases, the uterus is spared before the 6th month of pregnancy, and beyond that data caesarean section is mandatory.