Publications by authors named "P Govender"

Introduction: South Africa has endeavored to provide access to rehabilitation to more people with the greatest needs via its National Rehabilitation Policy. To achieve the aim of the Framework and Strategy for Disability and Rehabilitation Services in South Africa, scientific knowledge on rehabilitation services would be essential to inform implementation, yet little is known in the KwaZulu-Natal (KZN) province. This paper describes South African rehabilitation services delivery focused on availability, accessibility, quality, affordability, equity, effectiveness, and efficiency based on stakeholders´ perspectives in KZN.

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Background: There are limited US Federal Drug Administration-approved medications and real-world data on sarcoidosis treatment in the United States. Concordance of practice patterns with guideline recommendations have not been well characterized.

Research Question: What are the practice patterns and factors associated with treatment for patients with sarcoidosis in the year following diagnosis?

Study Design And Methods: A retrospective analysis was conducted of patients with sarcoidosis from 2016 to 2022 using a multicenter, all-payer claims database (TriNetX).

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  • - Early diagnosis and treatment of axial spondyloarthritis (axSpA) are crucial due to common issues of underdiagnosis and overdiagnosis, with South African guidelines offering methods for screening and useful investigations.
  • - A multidisciplinary approach to managing axSpA is recommended, focusing on lifestyle changes like exercise, smoking cessation, and psychosocial support.
  • - The ankylosing spondylitis disease activity score is suggested to track disease activity, alongside a stepwise therapy algorithm, and there is advice for screening comorbidities and ensuring vaccinations.
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  • Differences in microbial communities across various body habitats, such as the gut, oral cavity, and skin, play a crucial role in human health, particularly in immune response and development.
  • * Various factors, including genetics, diet, lifestyle, and geography, contribute to distinct microbiome compositions among populations, with significant differences observed between Western (Caucasian) and non-Western (African and Asian) communities based on their dietary habits.
  • * Recent studies reveal that bacteriophage dynamics within the virome are linked to bacterial diversity, suggesting future research should explore the interplay between the bacteriome and virome for better understanding and treatment of diseases, especially given the increasing need for population-specific approaches in microbiome-based therapeutics.*
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Central venous obstructions that impedes catheter placement or results in catheter dysfunction is a significant problem for haemodialysis patients. Recanalization can be performed with an intent to restore central venous access, improve outflow from arteriovenous fistula or to relieve symptomatic venous obstructions. Sharp recanalization encompasses various interventional techniques using a sharp instrument to puncture through or bypass around a venous obstruction.

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