Publications by authors named "P Genay"
Endoluminal angioplasty of the popliteal artery. Review of 54 consecutive patients.
Eur J Vasc Endovasc Surg
December 2005
Article Synopsis
- The study focused on the effectiveness of endoluminal angioplasty for treating occlusive or stenotic lesions in the popliteal artery.
- A total of 54 angioplasty procedures were conducted on 50 patients, showing a primary patency rate of 57.4% at 1 and 2 years, with better outcomes for patients with intermittent claudication and single lesions.
- The findings suggest that angioplasty is a viable treatment option for claudicants, particularly for certain lesions located in the distal part of the popliteal artery.
The thermodynamic ionization constants (pK(a)(1), pK(a)(2), and pK(a)(3)) of ginkgolide B (9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo-[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12-(4H)-trione, 3-tert-butylhexahydro-4,7b,11-trihydroxy-8-methyl-) in aqueous solution have been settled by pH-metric and NMR studies. The three macroscopic pK(a) values as well as the water solubility and the water/n-octanol partition coefficient have been extracted from pH-metric data by means of a nonlinear regression methodology. NMR spectroscopy provided confirmation of the values of the macroscopic constants, information about the effective ionization pathways, and an estimation of the proportions of the various forms under physiologically relevant conditions.
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