Publications by authors named "P Gayathri"
Top 100 most cited economic evaluation papers of preventive oral health programmes: A bibliometric analysis.
J Oral Biol Craniofac Res
November 2024
Objective: To identify the trends of the top 100 cited articles on economic evaluation in preventive oral health programs.
Methods: Top 100 papers involving economic evaluation or cost analysis of preventive oral health programs were selected by querying Scopus and Web of Science databases. Bibliometric analysis was performed using the Bibliometrix tool in R Studio.
Article Synopsis
- - MreB is an important protein in bacteria that helps maintain cell shape, and understanding its dynamics and interactions with membranes is crucial for studying bacterial biology.
- - Research has been limited due to challenges in purifying MreB, but scientists successfully extracted it from a bacteria called ScMreB5 using E. coli, achieving high concentrations of the stable protein for further study.
- - The developed purification protocol not only enhances protein yield and stability through optimized buffer conditions but also provides insights into how ions affect protein stability, which can be applied to other similar proteins.
Article Synopsis
- FtsZ is a crucial protein that forms a ring during bacterial cell division, marking it as a potential target for new antibiotics to fight resistance.
- The most effective inhibitor of FtsZ, PC190723, works against various Staphylococcus strains but shows resistance in others like E. coli.
- This study identifies specific interactions between FtsZ residues that prevent PC190723 from binding, and mutations in those areas increase E. coli's sensitivity to the inhibitor, suggesting a way to enhance its effectiveness against resistant bacteria.
Oral squamous cell carcinoma (OSCC) is indeed one of the most common types of oral cancer, typically affecting individuals over the age of 50. It primarily originates from the squamous epithelial cells lining the oral cavity. While it is relatively rare in individuals under 40 years old, it can still occur, albeit less frequently in that age group.
View Article and Find Full Text PDFFtsZ, the tubulin homolog essential for bacterial cell division, assembles as the Z-ring at the division site, and directs peptidoglycan synthesis by treadmilling. It is unclear how FtsZ achieves kinetic polarity that drives treadmilling. To obtain insights into fundamental features of FtsZ assembly dynamics independent of peptidoglycan synthesis, we carried out structural and biochemical characterization of FtsZ from the cell wall-less bacteria, Spiroplasma melliferum (SmFtsZ).
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