Tricuspid valve endocarditis with Group B Streptococcus after an elective abortion: the need for new data.

Streptococcus agalactiae, commonly known as Group B streptococcus (GBS), was originally discovered as a cause of bovine mastitis. GBS colonizes the genital tract of up to 40% of women and has become a major pathogen in neonatal meningitis. GBS endocarditis is thought to be an uncommon manifestation of this infection and carries a higher mortality compared to other streptococcal pathogens.

Diagnosis of primary HIV-1 infection. Los Angeles County Primary HIV Infection Recruitment Network.

Background: The optimal approach for diagnosing primary HIV-1 infection has not been defined.

Objective: To determine the usefulness of symptoms and virologic tests for diagnosing primary HIV-1 infection.

Design: Prospective cohort study.

Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase I-II escalating dosage trial.

Study Objective: To study the safety and pharmacokinetics and to derive preliminary evidence on surrogate indicators of efficacy of recombinant soluble CD4 (rsCD4) in patients with the acquired immunodeficiency syndrome (AIDS) and advanced AIDS-related complex.

Design: Open label, escalating dosage, phase I-II tolerance trial.

Setting: Massachusetts General Hospital, Cedars-Sinai Medical Center, and Stanford University Medical School, three tertiary care institutions and members of the National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group.