Publications by authors named "P Gasqui"
The tick Ixodes ricinus is widely distributed across Europe and is responsible for the transmission of several pathogens to humans and animals. In this study, we used a knowledge-based method to map variations in habitat suitability for I. ricinus ticks throughout continental France and Corsica.
View Article and Find Full Text PDFBackground: Ticks transmit pathogens of medical and veterinary importance and are an increasing threat to human and animal health. Assessing disease risk and developing new control strategies requires identifying members of the tick-borne microbiota as well as their temporal dynamics and interactions.
Methods: Using high-throughput sequencing, we studied the Ixodes ricinus microbiota and its temporal dynamics.
ELISA methods are the diagnostic tools recommended for the serological diagnosis of Coxiella burnetii infection in ruminants but their respective diagnostic performances are difficult to assess because of the absence of a gold standard. This study focused on three commercial ELISA tests with the following objectives (1) assess their sensitivity and specificity in sheep, goats and cattle, (2) assess the between- and within-herd seroprevalence distribution in these species, accounting for diagnostic errors, and (3) estimate optimal sample sizes considering sensitivity and specificity at herd level. We comparatively tested 1413 cattle, 1474 goat and 1432 sheep serum samples collected in France.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on how microbial interactions shape microbiota properties, emphasizing the challenges posed by the rarity of many operational taxonomic units (OTUs) within these communities.
- It highlights that traditional methods for detecting associations between OTUs often yield unreliable results due to a high number of zeros in the data tables.
- The authors propose a new approach to identify testable associations, which could enhance data analysis and network inference quality, ultimately aiding in the search for biological agents to manage rare pathogens.
Article Synopsis
- Q fever is a disease caused by the bacteria Coxiella burnetii that primarily affects ruminant animals and can be transmitted to humans through inhalation of contaminated aerosols.
- * The study aimed to analyze dust samples from various farm buildings to assess the presence and amount of C. burnetii, especially in relation to cases of abortions in animals, which may indicate Q fever outbreaks.
- * Results indicated that C. burnetii DNA was more frequently detected on sheep and goat farms compared to cattle farms, suggesting that these environments could serve as indicators of possible contamination.