Publications by authors named "P Gantner"

Article Synopsis
  • Tick-borne encephalitis (TBE) is caused by the TBE virus and typically presents milder symptoms in children, yet there's limited data on its incidence in this age group.* -
  • A study at the University Hospital of Strasbourg identified four confirmed cases of TBE among pediatric patients from 2020 to 2022, resulting in an incidence rate of 1.51 cases per 100,000 inhabitants.* -
  • The findings emphasize the importance of early diagnosis and follow-up care for affected children, as well as reconsidering vaccination guidelines due to observed cases among unvaccinated patients.*
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Developing effective vaccines is necessary in combating new virus pandemics. For HIV and SARS-CoV-2, the induction of neutralizing antibodies (NAb) is important for vaccine protection; however, the exact mechanisms underlying protection require further study. Recent data emphasize that even Abs that do not exhibit neutralizing activity may contribute to immune defense.

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Background: Vector-borne diseases such as malaria and arboviruses are common etiologies of post-travel fever.

Methods: After excluding malaria, we retrospectively analyzed the diagnosis of dengue virus (DENV), chikungunya virus (CHIKV), and zika virus (ZIKV) infections following recent travel by patients treated at the Strasbourg University Hospital between 2014 and 2023. Available serums (n = 35) sampled in 2023 were retrospectively tested for DENV, CHIKV, and ZIKV infections.

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Background: Throughout HIV infection, productively infected cells generate billions of viral particles and are thus responsible for body-wide HIV dissemination, but their phenotype during AIDS is unknown. As AIDS is associated with immunological changes, analyzing the phenotype of productively infected cells can help understand HIV production during this terminal stage.

Methods: Blood samples from 15 untreated viremic participants (recent infection, n=5; long-term infection, n=5; active opportunistic AIDS-defining disease, n=5) and 5 participants virologically controlled on antiretroviral therapy (ART) enrolled in the Analysis of the Persistence, Reservoir and HIV Latency (APRIL) study (NCT05752318) were analyzed.

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