Publications by authors named "P G Thadani"
Article Synopsis
- Polycystic ovary syndrome (PCOS) is a leading cause of infertility due to a lack of ovulation, and obesity worsens these reproductive issues; bariatric surgery might improve fertility rates but hasn't been vigorously tested against other treatments.
- This study involved 80 women with PCOS and obesity, who were randomly assigned to either undergo bariatric surgery (vertical sleeve gastrectomy) or receive behavioral and medical therapy to compare their impact on ovulation rates over a year.
- The study aimed to track the number of confirmed ovulatory events through regular progesterone testing, with results pending since participants were recruited between February 2020 and February 2021, and some participants dropped out of the trial.
Purpose: There is limited data regarding Pituitary Stalk Interruption Syndrome (PSIS) from India. Moreover, the pathophysiological link between perinatal events and PSIS is unclear. We aim to elucidate the predictors of PSIS among patients with growth hormone deficiency (GHD) and perinatal events in PSIS by comparing cohorts of PSIS and genetically proven GHD without PSIS.
View Article and Find Full Text PDFMost medial stabilized (MS) total knee arthroplasty (TKA) implants recommend excision of the posterior cruciate ligament (PCL), which eliminates the ligament's tension effect on the tibia that drives tibial rotation and compromises passive internal tibial rotation in flexion. Whether increasing the insert thickness and reducing the posterior tibial slope corrects the loss of rotation without extension loss and undesirable anterior lift-off of the insert is unknown. In 10 fresh-frozen cadaveric knees, an MS design with a medial ball-in-socket (i.
View Article and Find Full Text PDFContext: POU1F1 mutations are prevalent in Indian CPHD cohorts. Genotype-phenotype correlation is not well-studied.
Aim: To describe phenotypic and genotypic spectrum of POU1F1 mutations in our CPHD cohort and present systematic review as well as genotype-phenotype analysis of all mutation-positive cases reported in world literature.
Context: Regional variation in prevalence of genetic mutations in growth hormone deficiency (GHD) is known.
Aim: Study phenotype and prevalence of mutations in GH1, GHRHR, POU1F1, PROP1 genes in GHD cohort.
Methods: One hundred and two patients {Isolated GHD (IGHD): 79; combined pituitary hormone deficiency (CPHD): 23} with orthotopic posterior pituitary were included.