Publications by authors named "P G Stock"
Background: In November 2023, in the context of the Spanish Presidency of the Council of the European Union, the Organization National de Transplante organized a global summit discussing global action in transplantation for the next decade. This article reports the recommendations supporting the need to prioritize transplantation in healthcare systems.
Methods: The working group investigated how transplantation addresses noncommunicable disease mortality, particularly related to kidney and liver disease.
Article Synopsis
- Kidney transplantation from HIV-positive donors to HIV-positive recipients is a growing practice, initiated under a 2016 U.S. law, and is currently being evaluated for broader clinical implementation.
- An observational study involving 408 candidates at 26 U.S. centers assessed the safety and health outcomes of kidney transplants from both HIV-positive and HIV-negative donors to HIV-positive recipients, finding no significant difference in major health risks between the two donor groups.
- Results indicated similar long-term survival rates, graft success, and complication rates across both groups, although recipients of kidneys from HIV-positive donors showed a higher incidence of HIV breakthrough infections.
Article Synopsis
- Pancreas transplantation can enhance blood sugar control and reduce death rates in diabetes patients, but it requires strong immunosuppressive drugs to combat immune responses.
- The study evaluated the effectiveness of the tissue Common Response Module (tCRM) score and other biomarkers in assessing acute cellular rejection in pancreas transplants.
- Analysis of pancreas biopsies revealed significant gene expression changes linked to rejection severity, indicating that higher tCRM scores correlate with more severe rejection, and can differentiate between treatment-resistant and successfully treated cases.
This study aimed to investigate the effects of documentation status on pediatric kidney transplant outcomes in a single-center setting, emphasizing the significance of state insurance access for undocumented patients and federal policies like Deferred Action for Childhood Arrivals (DACA) on patient outcomes. A cohort of 283 patients, including 48 undocumented individuals, who received their first kidney transplant as children between 1998 and 2011 was analyzed. There was no significant difference in unadjusted all-cause (P = .
View Article and Find Full Text PDF