Publications by authors named "P G Pryde"
Article Synopsis
- Uterine clostridial myonecrosis is a rare but deadly infection, highlighted by two cases of maternal mortality linked to Clostridium bacteria during childbirth and medication abortion.
- The first case involved a 30-year-old woman with septic shock after labor complications, while the second case involved an adolescent who developed septic shock post-abortion, with both patients dying shortly after hospital admission.
- Timely diagnosis and treatment are critical, requiring quick identification of symptoms and immediate surgical action, such as hysterectomy, along with antibiotics to improve survival chances and prevent fatal outcomes.
Objective: To systematically review the evidence for the effectiveness and safety of magnesium sulfate as a fetal neuroprotective agent when given to individuals at risk of preterm birth.
Data Sources: We searched Cochrane Pregnancy and Childbirth's Trials Register, ClinicalTrials.gov , the World Health Organization International Clinical Trials Registry Platform (through March 17, 2023), and reference lists of relevant studies.
Background: Magnesium sulphate is a common therapy in perinatal care. Its benefits when given to women at risk of preterm birth for fetal neuroprotection (prevention of cerebral palsy for children) were shown in a 2009 Cochrane review. Internationally, use of magnesium sulphate for preterm cerebral palsy prevention is now recommended practice.
View Article and Find Full Text PDFThe aim of this study was to measure the effect of obesity and systemic opioids on respiratory events within the first 24 hours following cesarean. Opioid-naive women undergoing cesarean between January 2016 and December 2017 were included in this retrospective cohort study. The primary outcome was the proportion of women experiencing at least one composite respiratory outcome (oxygen saturation less than 95% lasting 30+ seconds or need for respiratory support) within 24 hours of cesarean.
View Article and Find Full Text PDF