: The COVID-19 pandemic affected antimicrobial stewardship in healthcare, including Skilled Nursing Facilities (SNFs). This study aimed to (1) assess the appropriateness of antibiotic prescriptions for urinary tract infections (UTIs) and respiratory tract infections (RTIs) and identify predictors of inappropriate use; (2) analyze changes in prescribing practices relative to the pandemic's onset. : A retrospective review of electronic medical records from a 300-bed SNF (March 2019-March 2021) identified suspected UTIs and RTIs based on laboratory tests and antibiotic requests.
View Article and Find Full Text PDFIntroduction: Fear of progression (FOP) is a significant psychological concern among cancer patients. The Fear of Progression Questionnaire-Short Form (FOPQ-SF) is one of the significant and reliable tools to evaluate FOP. This study aims to validate the psychometric features of the Persian version of FOPQ-SF in Iranian cancer patients.
View Article and Find Full Text PDFAs a model organism in the study of immunity to infection, has been instrumental in establishing key principles of host anti-microbial defense and its regulation. Here, we employed an attenuated uracil auxotroph strain of Type I designated OMP to further untangle the early immune response to this parasitic pathogen. Experiments using αβ T cell-deficient mice unexpectedly revealed that an intact αβ T lymphocyte compartment was essential to survive infection with OMP.
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