Publications by authors named "P G Montaldo"
Objective: To evaluate the accuracy of a device for continuous glucose monitoring (CGM) among infants born preterm admitted to the neonatal intensive care unit.
Study Design: We analyzed paired CGM sensor glucose (SG) and point-of-care blood glucose (BG) measurements collected in infants born at ≤32 weeks of gestation or with a birth weight ≤1500 g. CGM was initiated within 48 hours from birth and maintained for 5 days.
Article Synopsis
- The COMET trial aims to determine if whole-body hypothermia can improve cognitive development in neonates with mild hypoxic ischemic encephalopathy, a condition linked to learning difficulties.
- It is a phase III multicenter randomized controlled trial involving 426 neonates, comparing hypothermia treatment (33.5°C) to normothermia (37.0°C) within the first six hours of birth.
- The primary goal is to evaluate cognitive outcomes at two years using the Bayley scales, while also ensuring the trial's safety and assessing healthcare resource utilization.
Sequential levetiracetam and phenytoin in electroencephalographic neonatal seizures unresponsive to phenobarbital: a multicenter prospective observational study in India.
Lancet Reg Health Southeast Asia
June 2024
Background: Although levetiracetam and phenytoin are widely used antiseizure medications (ASM) in neonates, their efficacy on seizure freedom is unclear. We evaluated electroencephalographic (EEG) seizure freedom following sequential levetiracetam and phenytoin in neonatal seizures unresponsive to phenobarbital.
Methods: We recruited neonates born ≥35 weeks and aged <72 h who had continued electrographic seizures despite phenobarbital, from three Indian hospitals, between 20 June 2020 and 31 July 2022.