Molecular Detection of Virulence-Associated Markers in and Isolates From Water, Cattle, and Chicken Faecal Samples From Kajiado County, Kenya.

is a zoonotic foodborne pathogen that is often linked with gastroenteritis and other extraintestinal infections in humans. This study is aimed at determining the genetic determinants of virulence-encoding genes responsible for flagellin motility protein A (), adhesion to fibronectin F (), invasion antigen B () and cytolethal distending toxin (cdt) A () in species. A total of 29 isolates (16 from cattle, 9 from chicken, and 4 from water samples) and 74 isolates (38 from cattle, 30 from chicken, and 6 from water samples) described in an earlier study in Kajiado County, Kenya, were examined for the occurrence of virulence-associated genes using polymerase chain reaction (PCR) and amplicon sequencing.

Exploring nature's antidote: unveiling the inhibitory potential of selected medicinal plants from Kisumu, Kenya against venom from some snakes of medical significance in sub-Saharan Africa.

The present study investigated the efficacy of and against venom (BAV), venom (NAV), and venom (NSV). 40 extracts and fractions were prepared using n-hexane, dichloromethane, ethyl acetate, and methanol. efficacy against snake venom phospholipase A (svPLA) was determined in 96-well microtiter and agarose-egg yolk coagulation assays.

Antimicrobial Usage, Susceptibility Profiles, and Resistance Genes in Isolated from Cattle, Chicken, and Water Samples in Kajiado County, Kenya.

organisms are the major cause of bacterial gastroenteritis and diarrhoeal illness in man and livestock. is growingly becoming resistant to critically crucial antibiotics; thereby presenting public health challenge. This study aimed at establishing antimicrobial use, susceptibility profiles, and resistance genes in isolates recovered from chicken, cattle, and cattle-trough water samples.

Seasonal Prevalence and Molecular Identification of Thermophilic from Chicken, Cattle, and Respective Drinking Water in Kajiado County, Kenya.

Thermophilic species are a leading cause of human gastroenteritis throughout the world and have been implicated in reproductive disorders (abortion), mastitis, enteritis, and/or diarrhoea in livestock. A cross-sectional survey was conducted in Kajiado County to determine prevalence, seasonality, and molecular detection of thermophilic species (with emphasis on . , .

Preclinical efficacy testing of three antivenoms against venom-induced lethality.

This study aimed to determine the efficacy of Inoserp, Vins bioproducts, and South African Institute of Medical Research (SAIMR) polyvalent antivenoms in neutralizing venom-induced lethality in mice. The neutralization efficacy of the antivenoms were expressed as effective dose, median effective ratio, potency, normalized potency, volume, and the number of vials of antivenom required to neutralize 100 mg of venom (NAV).