Publications by authors named "P G Choe"
Background: Because patients infected with respiratory syncytial virus (RSV) have been reported to be older than patients infected with influenza virus, the more frequent incidence of complications in RSV-infected patients may be age-related. This study compared clinical characteristics and outcomes in hospitalized adults infected with RSV with findings in age- and sex-matched adults infected with influenza virus.
Methods: The medical records of hospitalized adult patients infected with RSV or influenza virus at two university hospitals from 2013 to 2022 were retrospectively analyzed.
Risk of nosocomial coronavirus disease 2019: comparison between single- and multiple-occupancy rooms.
Antimicrob Resist Infect Control
August 2024
Background: There is an ongoing controversy regarding whether single-occupancy rooms are superior to multiple-occupancy rooms in terms of infection prevention. We investigated whether treatment in a multiple-occupancy room is associated with an increased incidence of nosocomial coronavirus disease 2019 (COVID-19) compared with treatment in a single-occupancy room.
Methods: In this retrospective cohort study, every hospitalization period of adult patients aged ≥ 18 years at a tertiary hospital in Korea from January 1, 2022, to December 31, 2022, was analyzed.
While severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is characterized by impaired induction of interferons (IFNs) and IFN-stimulated genes (ISGs), the IFNs and ISGs in upper airway is essential to restrict the spread of respiratory virus. Here, we identified the prominent IFN and ISG upregulation in the nasopharynx (NP) of mild and even severe coronavirus disease 2019 (COVID-19) patients (CoV2+) in Omicron era and to compare their clinical outcome depending on the level of IFNs and ISGs. Whereas the induction of IFNB was minimal, transcription of IFNA, IFNG, and IFNLs was significantly increased in the NP of CoV2 + patients.
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- - The effectiveness of treating sepsis heavily relies on quickly giving the right antibiotics; however, current methods for determining the best treatment are slow, primarily due to lengthy blood culture processes.
- - A new ultra-rapid antimicrobial susceptibility testing (AST) method bypasses traditional blood cultures, potentially speeding up reporting times by 40-60 hours for drug susceptibility profiles.
- - This innovative approach uses a synthetic peptide to recover a wide range of pathogens from whole blood, achieving 100% species identification accuracy in a study with 190 patients, and a 94.90% agreement rate for AST results within an average of 13 hours after blood processing.
Article Synopsis
- The study investigates when to use echocardiography to check for infective endocarditis (IE) in patients with bloodstream infections caused by viridans group streptococci (VGS).
- It identifies key risk factors for IE, finding that heart valve disease, persistent bacteria in the blood, younger age, and infections from specific VGS species significantly increase risk.
- The findings suggest that echocardiography should be considered for patients showing these risk factors, to improve diagnosis and management of potential IE cases.