Publications by authors named "P G Bhavani"
Article Synopsis
- Metal toxicity impacts plant physiology, and mycorrhizal fungi (AMF) offer a new eco-friendly method to improve soil contaminated by tannery effluents, which are high in harmful metals like chromium and cadmium.* -
- A study was conducted using vetiver grass and three strains of AMF on contaminated soil from Tamil Nadu, revealing that AMF inoculation, particularly with R. intraradices, boosted plant growth and biomass significantly compared to other treatments.* -
- Results indicated that R. intraradices improved the phytoextraction of metals, reduced their movement into plant shoots, and increased carbon storage in vetiver, enhancing overall carbon sequestration in contaminated soil.*
Background: Antimicrobial peptides are an important component of host defense against Mycobacterium tuberculosis. However, the ability of BCG to induce AMPs as part of its mechanism of action has not been investigated in detail.
Methods: We investigated the impact of Bacillus Calmette-Guerin (BCG) vaccination on circulating plasma levels and TB-antigen stimulated plasma levels of AMPs in a healthy elderly population.
Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysis.
Trop Med Int Health
September 2024
Article Synopsis
- The study aimed to examine the prevalence of non-communicable diseases, particularly diabetes, among household contacts of individuals with tuberculosis (TB).
- A systematic review identified 39 studies, with 14 providing individual participant data and 25 offering aggregated data; the results showed a pooled diabetes prevalence of 8.8% among those tested properly.
- Findings indicate that diabetes prevalence among household contacts is likely underestimated, highlighting the importance of targeted interventions during TB contact investigations to identify and address these health issues.
Lamivudine (LMD), an enantiomer of 2'-deoxy-3'-thiacytidine, plays a crucial role in combatting HIV-1 and managing hepatitis B virus infections. Despite its effectiveness, challenges arise from its difficult flowability and tendency to agglomerate during storage, necessitating a granulation step before tablet compression, as direct compression has proven ineffective. This study aimed to optimize Lamivudine spherical agglomerates using response surface methodology, delving into the intricate relationship between design factors (concentration of tween, span, and acetone) and experimental outcomes (yield and particle size) through central composite design.
View Article and Find Full Text PDFBackground This study investigates the functional outcomes of single-bundle arthroscopic anterior cruciate ligament (ACL) reconstruction, comparing the use of two distinct graft sources: peroneus longus (PL) graft and hamstring graft. The choice of graft material in ACL reconstruction is crucial for optimal postoperative results, and this study aims to contribute valuable insights into the comparative efficacy of these two graft types. Method This open-label randomized comparative study involved a carefully selected cohort of patients undergoing single-bundle arthroscopic ACL reconstruction.
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