Publications by authors named "P Ford Combs"

Purpose: The specific aim of the study was to determine whether there was an increased time in target glucose range for individuals with type 1 diabetes mellitus who were permitted to self-manage their insulin plan while hospitalized.

Design: A retrospective chart review was conducted of 60 inpatients with type 1 diabetes mellitus who met the criteria to self-manage their diabetes care with the use of their continuous subcutaneous insulin infusion pump or a multiple daily injection insulin regimen. A comparison of the 2 groups was examined to assess differences in glucose outcomes and glycemic stability.

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Article Synopsis
  • A study was conducted to see how starting a sodium-glucose cotransporter-2 inhibitor (SGLT-2i) affects health status in adults with type 2 diabetes and cardiovascular disease, using data from 14 US hospitals between 2019 and 2021.!
  • Results showed that there was no significant difference in overall diabetes treatment satisfaction between SGLT-2i users and users of other diabetes medications after 6 months.!
  • However, SGLT-2i users experienced a greater reduction in ophthalmological symptoms and total diabetes symptom burden, particularly among patients with heart failure, but less improvement in hyperglycemia compared to other medication users.!
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Inference of toxicological and mechanistic properties of untested chemicals through structural or biological similarity is a commonly employed approach for initial chemical characterization and hypothesis generation. We previously developed a web-based application, Tox21Enricher-Grails, on the Grails framework that identifies enriched biological/toxicological properties of chemical sets for the purpose of inferring properties of untested chemicals within the set. It was able to detect significantly overrepresented biological (e.

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Despite the high prevalence of sleep disturbance in the heart failure population, information about its consequence on daytime function in patients with left-ventricular assist devices (LVADs) is limited. This study examined the nighttime and daytime sleep patterns and changes from pre-implant to 6 months post-implant. This study included 32 LVAD patients.

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