Publications by authors named "P Finch"
Article Synopsis
- Capsaicin, the active component in chili peppers, has strong pain-relieving properties and shows promise in slowing down the growth of certain cancers, particularly in gynecological types like cervical and ovarian cancers.
- The challenges in using capsaicin as an anti-cancer drug include its low absorption in the body and side effects such as stomach irritation and nausea.
- Research efforts are focused on improving capsaicin delivery through sustained release systems and creating non-pungent versions, potentially leading to new treatments for gynecological cancers.
Article Synopsis
- The European stag beetle (Lucanus cervus) is one of the largest beetles in Europe but is now near-threatened due to habitat loss, necessitating a monitoring system for future population trends.
- A study focused on the chemical ecology of this beetle aims to create a semiochemical-based monitoring system for effective conservation efforts in the UK and beyond.
- The research uncovered a unique male-produced pheromone that triggers sexual receptivity in females, a first in the animal kingdom, and clarified the role of a previously identified female-specific compound as a sex pheromone.
Persistent regional and systemic inflammation may promote pain and hyperalgesia in complex regional pain syndrome (CRPS). In this study, we investigated whether stimulation of α-adrenoceptors (α-AR) on peripheral blood mononuclear cells (PBMC) might contribute to this inflammatory state. PBMC were isolated from venous blood collected from 21 CRPS patients and 21 sex and age-matched controls.
View Article and Find Full Text PDFThe heterocyclic vanilloid compound capsaicin is responsible for the spicy and pungent flavor of chili peppers. Several convergent studies have shown that capsaicin suppresses the growth of multiple human cancers. Apart from capsaicin, natural and synthetic capsaicin-like compounds display growth suppressive activity in human cancers.
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