Enhanced frontoparietal synchronized activation during the wake-sleep transition in patients with primary insomnia.

Introduction: Cognitive and brain hyperactivation have been associated with trouble falling asleep and sleep misperception in patients with primary insomnia (PI). Activation and synchronization/temporal coupling in frontal and frontoparietal regions involved in executive control and endogenous attention might be implicated in these symptoms.

Methods: Standard polysomnography (PSG) and electroencephalogram (EEG) were recorded in 10 unmedicated young patients (age 19-34 yr) with PI with no other sleep/medical condition, and in 10 matched control subjects.

A pre-task resting condition neither 'baseline' nor 'zero'.

This study introduce the comparison of a 'reference state' versus a resting condition (zero), defined upon normative developmental equations. We compared pre-task 'resting' data from healthy individuals with the Normative Cuban digital resting EEG-database recently calculated for VARETA (qEEG/VARETA). The results allowed us to state that a 'pre-task resting conditions' exists as a state beyond the 'zero' or 'baseline' condition.

[Interictal EEG coherence in patients with partial temporal lobe epilepsy].

Aims: The purpose of this research was to study the spatio-temporal characteristics of the correlation that exists between two simultaneous EEG signals (coherence) in the interictal period in patients with partial epilepsy that is presumably symptomatic of the temporal lobe (ILAE).

Patients And Methods: A study of 13 patients, aged between 17-60 years, was conducted (53% females). A digital EEG was performed on each patient using the 10/20 system of electrode location.

Dynamic event-related potentials and rapid source analysis reveals an intermittent short-lasting dysfrontality in schizophrenia.

Neuroimaging studies have identified regional brain dysfunctions in schizophrenia, but their dynamic consequences remain unclear. This study reports electrophysiological evaluation of medicated schizophrenic patients during performance of the Wisconsin Card Sorting Test. Using event-related potentials (ERPs), averaged after passing through several band pass filters, and source analysis with variable-resolution brain electrical tomography, cerebral sources were visualized at every latency point of the evoked potential.

Abnormal functional asymmetry in occipital areas may prevent frontotemporal regions from achieving functional laterality during the WCST performance in patients with schizophrenia.

There is much evidence of frontotemporal lateralized abnormalities in schizophrenia. However, the relationship has not yet been examined between performance on the Wisconsin Card Sorting Test, with supposed anterior left dominance and event-related potential (ERP) asymmetry. ERPs recorded at homologous bilateral sites were compared using statistical permutation methods.