Annual SZ: An Alternative Immunotherapy for COVID-19 and Long COVID.

Since the outbreak of coronavirus disease 2019 (COVID-19) in late 2019 and early 2020, the identification of drugs to control severe acute respiratory syndrome coro-navirus 2 (SARS-CoV-2) infection and its symptoms has been a pressing focus of research. Cytokine storm and acute respiratory distress syndrome (ARDS) are the leading causes of mortality following infection. In this review, we discuss immune pathogenesis and four medications, including Remdesivir, Tocilizumab, Dexamethasone, and Annual SZ for COVID-19.

Impact of Low Maternal Weight on Pregnancy and Neonatal Outcomes.

Objective: To examine the effect of underweight maternal body mass index (BMI) on pregnancy complications and neonatal outcomes.

Design: Cohort study.

Setting: Tertiary academic center.

Sinonasal Outcomes after Endoscopic Pituitary Surgery in Patients With Cushing's Disease.

Purpose: The endoscopic endonasal approach (EEA) has become the preferred treatment for pituitary tumors, with minimal sinonasal morbidity. However, patients with Cushing's disease (CD) may represent a subgroup with prolonged impairment of sinonasal quality of life (QOL).

Methods: We retrospectively identified patients with CD who underwent EEA at our institution.

Impacts of radiation therapy on quality of life and pain relief in patients with bone metastases.

Bone metastases (BM) are a common complication in advanced cancer patients, significantly contributing to morbidity and mortality due to their ability to cause pain, fractures, and spinal cord compression. Radiation therapy (RT) is vital in managing these complications by targeting metastatic lesions to ease pain, improve mobility, and reduce the risk of skeletal-related events such as fractures. Evidence supports the effectiveness of RT in pain relief, showing its ability to provide significant palliation and lessen the need for opioid painkillers, thereby enhancing the overall quality of life (QoL) for patients with BM.