Respiratory diseases are important health problem throughout the world. The bronchoalveolar lavage (BAL) fluid obtained by fiber-optic bronchoscopy is a biofluid reflecting the expression of secreted pulmonary proteins and the products of activated cells. The characterization of the BALF proteome provides an opportunity to establish diagnostic and get prognostic indicators of airway diseases.
View Article and Find Full Text PDFThe vomeronasal organ is a chemosensory organ present in most vertebrates and involved in chemical communication. In the last decade, the deciphering of the signal transduction process of this organ has progressed. However, less is known about the vomeronasal organ ligands and their structure-function relationships.
View Article and Find Full Text PDFThe mineral, total amino acid, and sterol compositions of pollen collected by Apis mellifera L. were compared with the pollen of a plant consumed by Bombus terrestris (L.): Arbutus unedo L.
View Article and Find Full Text PDFJ Chromatogr B Analyt Technol Biomed Life Sci
February 2005
Lung diseases are essentially multi-factorial diseases that require a global analysis, and thus, cannot be understood through the sole analysis of individual or small numbers of genes. Proteome analysis has rapidly developed in the post-genome era and is now widely accepted as the obligated complementary technology for genetic profiling. It has been shown to be a powerful tool for the study of human diseases and for identifying novel prognostic, diagnostic and therapeutic markers.
View Article and Find Full Text PDFA proteome map of Ralstonia metallidurans strain CH34 was constructed using two-dimensional (2-D) gel electrophoresis in combination with automated Edman degradation and mass spectrometry (MS). R. metallidurans CH34 is the type-strain of a family of highly related strains characterized by their multiple resistance to millimolar amounts of heavy metals, conferred by two large plasmids.
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