Publications by authors named "P Faggioli"
Article Synopsis
- Lung transplantation (LuTx) is a crucial treatment for patients with systemic sclerosis (SSc) and severe lung disease, aiming to improve survival and overall health outcomes.
- A study of 13 SSc patients who underwent LuTx showed significant improvements in lung function, skin involvement, and overall disease activity over a two-year period.
- The survival rate at two years post-transplant was 92.3%, indicating LuTx is a promising option for SSc patients in advanced stages of the disease, with no unexpected adverse events reported.
Assessing SARS-CoV-2-specific T-cell reactivity in late convalescents and vaccinees: Comparison and combination of QuantiFERON and activation-induced marker assays, and relation with antibody status.
PLoS One
May 2023
Objectives: Monitoring of SARS-CoV-2 spread and vaccination strategies have relied on antibody (Ab) status as a correlate of protection. We used QuantiFERON™ (QFN) and Activation-Induced Marker (AIM) assays to measure memory T-cell reactivity in unvaccinated individuals with prior documented symptomatic infection (late convalescents) and fully vaccinated asymptomatic donors (vaccinees).
Methods: Twenty-two convalescents and 13 vaccinees were enrolled.
Article Synopsis
- The study evaluated the effectiveness of belimumab for treating joint and skin symptoms in patients with systemic lupus erythematosus (SLE) using specific metrics like DAS28 and CLASI.
- Results showed notable improvements, with increasing percentages of patients achieving remission in joint (DAS28) and skin (CLASI) symptoms over 24 months.
- Belimumab was also found to reduce the need for glucocorticoids, and early responders (by 6 months) had a higher chance of achieving remission later in the treatment.
Objective: To assess the feasibility of a new device for telemonitoring vital parameters during iloprost infusion.
Materials And Methods: In a pilot study, patients with systemic sclerosis received iloprost infusion while being telemonitored with Umana T1 Heart Monitor, within the hospital, under the supervision of family/community nurses and rheumatologists. Patients were administered a questionnaire to obtain information on satisfaction, practicability, and compliance with the new monitoring device.
Rheumatoid arthritis (RA) is a systemic inflammatory disease, which primarily causes symmetric polyarthritis. An extrarticolar involvement is common, and the commonly involved organ is lungs. Although cardiac disease is responsible for most RA-related deaths, pulmonary disease is also a major contributor, accounting for ~10-20% of all mortality.
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