Publications by authors named "P Faggiano"

Background: The reduction in long-term mortality after acute myocardial infarction (AMI) is less pronounced than that of in-hospital mortality among patients with AMI complicated by heart failure (HF) and/or in those with a high residual thrombotic risk (HTR).

Aim: To investigate the relative prognostic significance of HTR and HF in AMI survivors.

Methods: This retrospective cohort study enrolled patients admitted for AMI in 2014-2015 in all Italian hospitals.

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According to current guidelines, only clinical surveillance is recommended for patients with moderate aortic valve stenosis (AS), while aortic valve replacement may be considered in patients undergoing surgery for other indications. Recent studies have shown that moderate AS is associated with a high risk of adverse cardiovascular events, including death, especially in patients with left ventricular dysfunction. In this context, multimodality imaging can help to improve the accuracy of moderate AS diagnosis and to assess left ventricular remodeling response.

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Article Synopsis
  • - The study aimed to assess how the presence of raphe (a type of anatomical feature) in patients with bicuspid aortic valve (BAV) correlates with valve dysfunction, aortopathy, and the likelihood of needing aortic valve surgery.
  • - Researchers analyzed 695 BAV patients, finding that those with raphe experienced more moderate to severe aortic stenosis and a higher prevalence of aortopathy, particularly Type B, compared to those without raphe.
  • - The results indicated that having raphe significantly raises the odds of requiring aortic valve surgery within three years, highlighting the importance of monitoring patients with this anatomical feature.
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Article Synopsis
  • Epidemiologic, genetic, and clinical studies indicate that low-density lipoprotein cholesterol (LDL-C) plays a key role in developing atherosclerotic cardiovascular disease (ASCVD), but variability in LDL-C levels may increase ASCVD risk even in statin-treated patients.
  • A retrospective study followed 3,398 patients with stable cardiovascular disease for a median of 56 months, finding that the percentage achieving LDL-C levels below 70 mg/dL increased from 20.7% to 31.9%.
  • Results show that for every 20 mg/dL increase in LDL-C levels, the risk of any adverse event rose by 6%, emphasizing the importance of consistently lowering LDL-C for cardiovascular benefits in patients receiving
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