Metacognition in Children and Adolescents With Obsessive-Compulsive Disorder Treated With Cognitive Behavioral Therapy.

According to the metacognitive theory, maladaptive metacognition is associated with the development and maintenance of emotional disorders. This study is the first to explore maladaptive metacognition in a sample of children and adolescents (7-17 years) with obsessive-compulsive disorder (OCD) in the context of cognitive behavioral therapy (CBT). A total of 114 children and adolescents were included in the study.

The significance of DNA methylation of the gene encoding the glucocorticoid receptor for developing resilience in individuals exposed to early life stress.

Purpose: To analyze and interpret why some individuals are resilient to ELS while others are susceptible, resulting in psychiatric outcome later in life, with a focus on the role of DNAm of the gene as a mediating mechanism between ELS and the risk of psychiatric outcomes. We hypothesized that a high level of mental resilience to ELS, expressed as lower incidence of psychiatric outcomes, was associated with attenuated DNAm levels.

Materials And Methods: The first authors conducted a systematic search on PubMed to identify primary research studies.

Geographic variation of recorded neurodevelopmental disorders in children and adults.

Introduction: While diagnosis rates of autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD) vary within countries at a large-scale municipal level, small neighbourhood geographic variation remains understudied. In this nationwide study, we describe the rates of ASD and ADHD diagnoses in children and adults by geographical data zones of approximately 2,500 residents across Denmark.

Methods: We included a population of children born from 1993 through 2020 and an adult population born from 1977 through 2003.

Early-life cow-level risk factors for sole ulcers in primiparous dairy cows.

Sole ulcers negatively affect cow welfare and production economy. Previous cases of sole ulcers increase the risk of new or recurrent cases, and prevention of sole ulcers during the first lactation may therefore have a long-term effect, also in later lactations. Until now, risk factors for sole ulcers in the first lactation, associated with the period before heifers calve for the first time, have not been investigated.

The Core of the Matter-Importance of Identification Method and Biological Replication for Benthic Marine Monitoring.

Benthic macrofauna are important and widely used biological indicators of marine ecosystems as they have limited mobility and therefore integrate the effects of local environmental stressors over time. Recently, environmental DNA (eDNA) analysis has provided a potentially more resource-efficient approach for benthic biomonitoring than traditional morphology-based methods. Several studies have compared eDNA with morphology-based monitoring, but few have compared the two approaches using the exact same sediment cores.