[Experimental approach to the prophylaxis and treatment of acute lung injury syndrome with proteinase inhibitors and corvitin].

The results of a combined study of the proteolysis on a model of post-ischemic toxemia in rats showed a decrease in antiproteinase potential and an activation of proteolysis. The activation of proteolysis and inhibition of antiproteinases was observed not only in the blood, but also in the bronchoalveolar secretion. Those changes were accompanied with the changes in the morphological structure of the lungs.

[Changes in the local proteinase-inhibitor system in children with chronic erosive gastritis].

In 26 children presenting with chronic erosive gastritis, an unspecific proteinase-inhibitor potential was identified in the basal portion of the gastric juice in the period of exacerbation and incomplete remission. Revealed in the gastric content in the period of exacerbation was augmentation of the activity of elastase- and tripsinlike proteinases. In the period of remission, the indices have been shown to be lower but insignificantly, remaining significantly higher compared to those indices in the control group.